Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) Mus musculus
Analyze
Symbol: Ywhaz
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Description: Exhibits protein domain specific binding activity. Involved in several processes, including ERK1 and ERK2 cascade; synaptic target recognition; and tube morphogenesis. Localizes to hippocampal mossy fiber to CA3 synapse and nucleus. Used to study schizophrenia. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; histone modification pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110013I11Rik; 14-3-3 protein zeta/delta; 14-3-3 zeta; 14-3-3zeta; AI596267; AL022924; AU020854; KCIP-1; protein kinase C inhibitor protein 1; SEZ-2
Orthologs:
Related Pseudogenes: Gm19228   Gm5279  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1536,770,770 - 36,796,929 (-)EnsemblGRCm38mm10GRCm38
GRCm381536,770,261 - 36,802,984 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371536,700,016 - 36,724,293 (-)NCBIGRCm37mm9NCBIm37
MGSCv361536,715,359 - 36,738,833 (-)NCBImm8
Celera1537,392,750 - 37,416,932 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ywhaz
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11498
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.