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Gene: Yy1 (YY1 transcription factor) Mus musculus
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Symbol: Yy1
Name: YY1 transcription factor
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including camera-type eye morphogenesis; regulation of gene expression; and response to UV-C. Localizes to the nucleus; ribonucleoprotein complex; and transcription factor complex. Used to study pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in congestive heart failure. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; genitourinary system; and hemolymphoid system gland. Orthologous to human YY1 (YY1 transcription factor); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW488674; delta transcription factor; NF-E1; transcriptional repressor protein YY1; UCR-motif DNA-binding protein; UCRBP transcription factor; yin and yang 1; Yin Yang 1; YY-1
Orthologs:
Homo sapiens (human) : YY1 (YY1 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Yy1 (YY1 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yy1 (YY1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : YY1 (YY1 transcription factor)
Canis lupus familiaris (dog) : YY1 (YY1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yy1 (YY1 transcription factor)
Sus scrofa (pig) : YY1 (YY1 transcription factor)
Chlorocebus sabaeus (African green monkey) : YY1 (YY1 transcription factor)
Heterocephalus glaber (naked mole-rat) : Yy1 (YY1 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12108,792,973 - 108,820,148 (+)Ensembl
GRCm3812108,792,945 - 108,820,148 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712110,031,521 - 110,054,842 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612109,241,118 - 109,264,439 (+)NCBImm8
Celera12110,029,534 - 110,052,930 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Yy1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11500
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.