Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Yy1 (YY1 transcription factor) Mus musculus
Symbol: Yy1
Name: YY1 transcription factor
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including camera-type eye morphogenesis; regulation of gene expression; and response to UV-C. Localizes to the nucleus; ribonucleoprotein complex; and transcription factor complex. Used to study pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in congestive heart failure. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; genitourinary system; and hemolymphoid system gland. Orthologous to human YY1 (YY1 transcription factor); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW488674; delta transcription factor; NF-E1; transcriptional repressor protein YY1; UCR-motif DNA-binding protein; UCRBP transcription factor; yin and yang 1; Yin Yang 1; YY-1
Homo sapiens (human) : YY1 (YY1 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Yy1 (YY1 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yy1 (YY1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : YY1 (YY1 transcription factor)
Canis lupus familiaris (dog) : YY1 (YY1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yy1 (YY1 transcription factor)
Sus scrofa (pig) : YY1 (YY1 transcription factor)
Chlorocebus sabaeus (African green monkey) : YY1 (YY1 transcription factor)
Heterocephalus glaber (naked mole-rat) : Yy1 (YY1 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12108,792,973 - 108,820,148 (+)Ensembl
GRCm3812108,792,945 - 108,820,148 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712110,031,521 - 110,054,842 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612109,241,118 - 109,264,439 (+)NCBImm8
Celera12110,029,534 - 110,052,930 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Yy1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11500
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.