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Gene: Nlgn3em1Sage (neuroligin 3; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs) Rattus norvegicus
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Symbol: Nlgn3em1Sage
Name: neuroligin 3; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
Description: The ZFN mutant allele was produced by injecting zinc finger nuclease targeting rat Nlgn3 into Sprague Dawley embryos. The resulting mutation was a 58bp deletion of the exon5/intron 5 junction occurred at 9874bp-9931bp. Homozygous knockout rats exhibit complete loss of target protein as demonstrated by Western blot.
ASSOCIATED WITH abnormal social play behavior; decreased anxiety-related response; decreased body weight; ASSOCIATED WITH autism spectrum disorder
Type: allele  of Nlgn3  
Also known as: Nlgn3tm1Sage; Nlgn3em1Sage
Is Marker For: Strains:   SD-Nlgn3em1Sage  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position: No map positions available.


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Phenotype Annotations
References - curated

Genomics

Related Rat Strains

Expression


Sequence

Nucleotide Sequences

Additional Information

 
More on Nlgn3em1Sage
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Ensembl Gene
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CRRD Object Information
CRRD ID: 11568701
Created: 2016-12-13
Species: Rattus norvegicus
Last Modified: 2016-12-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.