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Gene: AGO3 (argonaute RISC catalytic component 3) Pan paniscus
Symbol: AGO3
Name: argonaute RISC catalytic component 3
Description: ENCODES a protein that exhibits double-stranded RNA binding (ortholog); endoribonuclease activity (ortholog); endoribonuclease activity, cleaving miRNA-paired mRNA (ortholog); INVOLVED IN miRNA loading onto RISC involved in gene silencing by miRNA (ortholog); miRNA mediated inhibition of translation (ortholog); mRNA catabolic process (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN condensed nuclear chromosome (ortholog); cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: argonaute 3, RISC catalytic component; EIF2C3; eukaryotic translation initiation factor 2C, 3
Homo sapiens (human) : AGO3 (argonaute RISC catalytic component 3)  HGNC  Alliance
Mus musculus (house mouse) : Ago3 (argonaute RISC catalytic subunit 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ago3 (argonaute RISC catalytic component 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago3 (argonaute RISC catalytic component 3)
Canis lupus familiaris (dog) : AGO3 (argonaute RISC catalytic component 3)
Sus scrofa (pig) : AGO3 (argonaute RISC catalytic component 3)
Chlorocebus sabaeus (African green monkey) : AGO3 (argonaute RISC catalytic component 3)
Heterocephalus glaber (naked mole-rat) : Ago3 (argonaute RISC catalytic component 3)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1 Ensembl136,372,221 - 36,497,190 (+)Ensemblpanpan1.1panPan2
PanPan1.1136,371,926 - 36,497,190 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on AGO3
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11781391
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.