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Gene: PTEN (phosphatase and tensin homolog) Pan paniscus
Symbol: PTEN
Name: phosphatase and tensin homolog
Description: This gene encodes a dual-specificity phosphatase that regulates the mitogen activated protein kinase pathway through its phosphatase activity and the phosphatidylinositol 3-kinase pathway through its lipid phosphatase activity. It was first identified because of its tumor suppressor activity, and mutations in this gene are associated with many types of cancers in mouse and human. [provided by RefSeq, May 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: mitochondrial PTENalpha; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Homo sapiens (human) : PTEN (phosphatase and tensin homolog)  HGNC  Alliance
Mus musculus (house mouse) : Pten (phosphatase and tensin homolog)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pten (phosphatase and tensin homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pten (phosphatase and tensin homolog)
Canis lupus familiaris (dog) : PTEN (phosphatase and tensin homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pten (phosphatase and tensin homolog)
Sus scrofa (pig) : PTEN (phosphatase and tensin homolog)
Chlorocebus sabaeus (African green monkey) : PTEN (phosphatase and tensin homolog)
Heterocephalus glaber (naked mole-rat) : Pten (phosphatase and tensin homolog)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1 Ensembl1088,093,539 - 88,194,605 (+)Ensemblpanpan1.1panPan2
PanPan1.11088,093,539 - 88,197,902 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on PTEN
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11834437
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.