DKK4 (dickkopf WNT signaling pathway inhibitor 4) - Chinchilla Research Resource Database
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Gene: DKK4 (dickkopf WNT signaling pathway inhibitor 4) Pan paniscus
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Symbol: DKK4
Name: dickkopf WNT signaling pathway inhibitor 4
CRRD ID: 11886529
Description: INVOLVED IN negative regulation of hair follicle placode formation (ortholog); Wnt signaling pathway (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH IMMUNODEFICIENCY 15 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dickkopf homolog 4; dickkopf-related protein 4
Orthologs:
Homo sapiens (human) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)  HGNC  Alliance
Mus musculus (house mouse) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)  Alliance
Canis lupus familiaris (dog) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
Sus scrofa (pig) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Chlorocebus sabaeus (African green monkey) : DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Heterocephalus glaber (naked mole-rat) : Dkk4 (dickkopf WNT signaling pathway inhibitor 4)
more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1839,062,711 - 39,082,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl839,062,711 - 39,082,575 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0841,618,173 - 41,638,550 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
DKK4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1839,062,711 - 39,082,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl839,062,711 - 39,082,575 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0841,618,173 - 41,638,550 (-)NCBIMhudiblu_PPA_v0panPan3
DKK4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl842,374,063 - 42,377,229 (-)EnsemblGRCh38hg38GRCh38
GRCh38842,373,194 - 42,391,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37842,231,586 - 42,234,674 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36842,350,743 - 42,353,831 (-)NCBINCBI36hg18NCBI36
Build 34842,350,743 - 42,353,830NCBI
Celera841,176,301 - 41,179,389 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef840,754,805 - 40,757,893 (-)NCBIHuRef
CHM1_1842,278,494 - 42,281,582 (-)NCBICHM1_1
Dkk4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,113,701 - 23,117,563 (+)NCBI
GRCm38822,623,685 - 22,628,018 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl822,624,043 - 22,627,547 (+)EnsemblGRCm38mm10GRCm38
MGSCv37823,734,515 - 23,738,019 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,089,588 - 24,093,092 (+)NCBImm8
Celera824,114,227 - 24,117,730 (+)NCBICelera
Cytogenetic Map8A2NCBI
Dkk4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01674,260,551 - 74,264,142 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1674,260,551 - 74,264,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,893,385 - 73,896,976 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,888,290 - 73,891,881 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1667,295,927 - 67,299,518 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
DKK4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1623,302,320 - 23,304,834 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11623,302,124 - 23,304,824 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dkk4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936785319,494 - 323,226 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DKK4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1711,390,206 - 11,394,268 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11711,389,551 - 11,394,754 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21712,989,140 - 12,992,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DKK4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl840,370,336 - 40,373,264 (-)Ensembl
ChlSab1.1840,370,299 - 40,386,835 (-)NCBI
Dkk4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624780873,669 - 884,091 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003823284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000043777   ⟹   ENSPPAP00000020978
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl839,062,711 - 39,082,575 (-)Ensembl
RefSeq Acc Id: XM_003823284   ⟹   XP_003823332
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1839,062,711 - 39,082,575 (-)NCBI
Mhudiblu_PPA_v0841,618,173 - 41,638,550 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823332 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003823332   ⟸   XM_003823284
- Sequence:
RefSeq Acc Id: ENSPPAP00000020978   ⟸   ENSPPAT00000043777
Protein Domains
Dickkopf_N   Prokineticin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000020978 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043777 UniProtKB/TrEMBL
InterPro Dickkopf_N UniProtKB/TrEMBL
  DKK-like UniProtKB/TrEMBL
  Prokineticin_domain UniProtKB/TrEMBL
KEGG Report pps:100989056 UniProtKB/TrEMBL
NCBI Gene DKK4 ENTREZGENE
PANTHER PTHR12113 UniProtKB/TrEMBL
Pfam Dickkopf_N UniProtKB/TrEMBL
  Prokineticin UniProtKB/TrEMBL
UniProt A0A2R9AUV2_PANPA UniProtKB/TrEMBL