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Gene: MLH1 (mutL homolog 1) Pan paniscus
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Symbol: MLH1
Name: mutL homolog 1
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATPase activity (ortholog); chromatin binding (ortholog); INVOLVED IN double-strand break repair via nonhomologous end joining (ortholog); female meiosis chromosome segregation (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); cervix uteri carcinoma in situ (ortholog); colon cancer (ortholog); FOUND IN chiasma (ortholog); late recombination nodule (ortholog); male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA mismatch repair protein Mlh1; mutL homolog 1, colon cancer, nonpolyposis type 2
Orthologs:
Homo sapiens (human) : MLH1 (mutL homolog 1)  HGNC  Alliance
Mus musculus (house mouse) : Mlh1 (mutL homolog 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mlh1 (mutL homolog 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlh1 (mutL homolog 1)
Canis lupus familiaris (dog) : MLH1 (mutL homolog 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlh1 (mutL homolog 1)
Sus scrofa (pig) : MLH1 (mutL homolog 1)
Chlorocebus sabaeus (African green monkey) : MLH1 (mutL homolog 1)
Heterocephalus glaber (naked mole-rat) : Mlh1 (mutL homolog 1)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1 Ensembl337,189,439 - 37,245,801 (+)Ensemblpanpan1.1panPan2
PanPan1.1337,189,439 - 37,245,801 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
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Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

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More on MLH1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11891842
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.