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Gene: MLH1 (mutL homolog 1) Pan paniscus
Symbol: MLH1
Name: mutL homolog 1
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATPase activity (ortholog); chromatin binding (ortholog); INVOLVED IN double-strand break repair via nonhomologous end joining (ortholog); female meiosis chromosome segregation (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); cervix uteri carcinoma in situ (ortholog); colon cancer (ortholog); FOUND IN chiasma (ortholog); late recombination nodule (ortholog); male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA mismatch repair protein Mlh1; mutL homolog 1, colon cancer, nonpolyposis type 2
Homo sapiens (human) : MLH1 (mutL homolog 1)  HGNC  Alliance
Mus musculus (house mouse) : Mlh1 (mutL homolog 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mlh1 (mutL homolog 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlh1 (mutL homolog 1)
Canis lupus familiaris (dog) : MLH1 (mutL homolog 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlh1 (mutL homolog 1)
Sus scrofa (pig) : MLH1 (mutL homolog 1)
Chlorocebus sabaeus (African green monkey) : MLH1 (mutL homolog 1)
Heterocephalus glaber (naked mole-rat) : Mlh1 (mutL homolog 1)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1 Ensembl337,189,439 - 37,245,801 (+)Ensemblpanpan1.1panPan2
PanPan1.1337,189,439 - 37,245,801 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on MLH1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11891842
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.