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Gene: LRRK2 (leucine rich repeat kinase 2) Pan paniscus
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Symbol: LRRK2
Name: leucine rich repeat kinase 2
Description: ENCODES a protein that exhibits actin binding (ortholog); beta-catenin destruction complex binding (ortholog); clathrin binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of MAPKK activity (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); cancer (ortholog); colitis (ortholog); FOUND IN amphisome (ortholog); autolysosome (ortholog); axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: leucine-rich repeat serine/threonine-protein kinase 2
Orthologs:
Homo sapiens (human) : LRRK2 (leucine rich repeat kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Lrrk2 (leucine-rich repeat kinase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lrrk2 (leucine-rich repeat kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrk2 (leucine rich repeat kinase 2)
Canis lupus familiaris (dog) : LRRK2 (leucine rich repeat kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrk2 (leucine rich repeat kinase 2)
Sus scrofa (pig) : LRRK2 (leucine rich repeat kinase 2)
Chlorocebus sabaeus (African green monkey) : LRRK2 (leucine rich repeat kinase 2)
Heterocephalus glaber (naked mole-rat) : Lrrk2 (leucine rich repeat kinase 2)
more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11249,205,930 - 49,350,462 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1249,205,930 - 49,350,462 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01248,343,621 - 48,488,337 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on LRRK2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11901385
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.