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Gene: APP (amyloid beta precursor protein) Pan paniscus
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Symbol: APP
Name: amyloid beta precursor protein
Description: ENCODES a protein that exhibits acetylcholine receptor activator activity (ortholog); acetylcholine receptor binding (ortholog); amylin binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of MAPKKK activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN Alzheimer's disease pathway; glypican signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 1 (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN amyloid-beta complex (ortholog); apical part of cell (ortholog); astrocyte projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: amyloid beta A4 protein-like; LOC100970102; LOC100971121
Orthologs:
Homo sapiens (human) : APP (amyloid beta precursor protein)  HGNC  Alliance
Mus musculus (house mouse) : App (amyloid beta (A4) precursor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : App (amyloid beta precursor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : App (amyloid beta precursor protein)
Canis lupus familiaris (dog) : APP (amyloid beta precursor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : App (amyloid beta precursor protein)
Sus scrofa (pig) : APP (amyloid beta precursor protein)
Chlorocebus sabaeus (African green monkey) : APP (amyloid beta precursor protein)
Heterocephalus glaber (naked mole-rat) : App (amyloid beta precursor protein)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1 Ensembl2125,684,355 - 25,995,072 (-)Ensemblpanpan1.1panPan2
PanPan1.12125,683,236 - 25,995,262 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
 
More on APP
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11944783
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.