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Gene: ERN1 (endoplasmic reticulum to nucleus signaling 1) Pan paniscus
Symbol: ERN1
Name: endoplasmic reticulum to nucleus signaling 1
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); endoribonuclease activity (ortholog); INVOLVED IN activation of JUN kinase activity (ortholog); cell cycle arrest (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN Alzheimer's disease pathway; endoplasmic reticulum stress - the unfolded protein response pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); epilepsy (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN AIP1-IRE1 complex (ortholog); cell (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: serine/threonine-protein kinase/endoribonuclease IRE1
Homo sapiens (human) : ERN1 (endoplasmic reticulum to nucleus signaling 1)  HGNC  Alliance
Mus musculus (house mouse) : Ern1 (endoplasmic reticulum (ER) to nucleus signalling 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ern1 (endoplasmic reticulum to nucleus signaling 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Canis lupus familiaris (dog) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Sus scrofa (pig) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Chlorocebus sabaeus (African green monkey) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Heterocephalus glaber (naked mole-rat) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1 Ensembl1763,226,949 - 63,317,825 (-)Ensemblpanpan1.1panPan2
PanPan1.11763,226,949 - 63,317,825 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on ERN1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11954907
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.