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Gene: IRS2 (insulin receptor substrate 2) Pan paniscus
Symbol: IRS2
Name: insulin receptor substrate 2
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); insulin receptor binding (ortholog); phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN brain development (ortholog); cellular response to glucose stimulus (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN erythropoietin signaling pathway; insulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Diabetes Mellitus, Experimental (ortholog); Diabetic Nephropathies (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: insulin receptor substrate 2
Homo sapiens (human) : IRS2 (insulin receptor substrate 2)  HGNC  Alliance
Mus musculus (house mouse) : Irs2 (insulin receptor substrate 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irs2 (insulin receptor substrate 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irs2 (insulin receptor substrate 2)
Canis lupus familiaris (dog) : IRS2 (insulin receptor substrate 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irs2 (insulin receptor substrate 2)
Sus scrofa (pig) : IRS2 (insulin receptor substrate 2)
Chlorocebus sabaeus (African green monkey) : IRS2 (insulin receptor substrate 2)
Heterocephalus glaber (naked mole-rat) : Irs2 (insulin receptor substrate 2)
more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.113110,013,214 - 110,044,465 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01390,886,095 - 90,917,724 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on IRS2
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 11975181
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.