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Gene: CD74 (CD74 molecule) Pan paniscus
Symbol: CD74
Name: CD74 molecule
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); CD4 receptor binding (ortholog); cytokine binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); antigen processing and presentation (ortholog); antigen processing and presentation of endogenous antigen (ortholog); PARTICIPATES IN antigen processing and presentation pathway; tuberculosis pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Breast Neoplasms (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell surface (ortholog); clathrin-coated endocytic vesicle membrane (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: HLA class II histocompatibility antigen gamma chain
Homo sapiens (human) : CD74 (CD74 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd74 (CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd74 (CD74 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd74 (CD74 molecule)
Canis lupus familiaris (dog) : CD74 (CD74 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd74 (CD74 molecule)
Sus scrofa (pig) : CD74 (CD74 molecule)
Chlorocebus sabaeus (African green monkey) : CD74 (CD74 molecule)
Heterocephalus glaber (naked mole-rat) : Cd74 (CD74 molecule)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1 Ensembl5151,830,311 - 151,841,334 (-)Ensemblpanpan1.1panPan2
PanPan1.15151,830,311 - 151,841,334 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on CD74
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12033974
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.