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Gene: ABCC1 (ATP binding cassette subfamily C member 1) Canis lupus familiaris
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Symbol: ABCC1
Name: ATP binding cassette subfamily C member 1
Description: ENCODES a protein that exhibits ABC-type transmembrane transporter activity (ortholog); ATPase-coupled glutathione S-conjugate transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN leukotriene transport (ortholog); positive regulation of inflammatory response (ortholog); response to drug (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN basal plasma membrane (inferred); integral component of membrane (inferred); integral component of plasma membrane (inferred); INTERACTS WITH calcein am; etoposide; leukotriene C4
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 1; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; LTC4 transporter; MRP1; multidrug resistance protein 1; multidrug resistance-associated protein 1
Orthologs:
Homo sapiens (human) : ABCC1 (ATP binding cassette subfamily C member 1)  HGNC  Alliance
Mus musculus (house mouse) : Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcc1 (ATP binding cassette subfamily C member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc1 (ATP binding cassette subfamily C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc1 (ATP binding cassette subfamily C member 1)
Sus scrofa (pig) : ABCC1 (ATP binding cassette subfamily C member 1)
Chlorocebus sabaeus (green monkey) : ABCC1 (ATP binding cassette subfamily C member 1)
Heterocephalus glaber (naked mole-rat) : Abcc1 (ATP binding cassette subfamily C member 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl627,855,702 - 27,989,331 (-)Ensembl
CanFam3.1627,855,702 - 27,950,140 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ABCC1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12050846
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.