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Gene: ABCC1 (ATP binding cassette subfamily C member 1) Canis lupus familiaris
Symbol: ABCC1
Name: ATP binding cassette subfamily C member 1
Description: ENCODES a protein that exhibits ABC-type transmembrane transporter activity (ortholog); ATPase-coupled glutathione S-conjugate transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN leukotriene transport (ortholog); positive regulation of inflammatory response (ortholog); response to drug (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN basal plasma membrane (inferred); integral component of membrane (inferred); integral component of plasma membrane (inferred); INTERACTS WITH calcein am; etoposide; leukotriene C4
Type: protein-coding
Also known as: ATP-binding cassette sub-family C member 1; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; LTC4 transporter; MRP1; multidrug resistance protein 1; multidrug resistance-associated protein 1
Homo sapiens (human) : ABCC1 (ATP binding cassette subfamily C member 1)  HGNC  Alliance
Mus musculus (house mouse) : Abcc1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcc1 (ATP binding cassette subfamily C member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc1 (ATP binding cassette subfamily C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc1 (ATP binding cassette subfamily C member 1)
Sus scrofa (pig) : ABCC1 (ATP binding cassette subfamily C member 1)
Chlorocebus sabaeus (green monkey) : ABCC1 (ATP binding cassette subfamily C member 1)
Heterocephalus glaber (naked mole-rat) : Abcc1 (ATP binding cassette subfamily C member 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl627,855,702 - 27,989,331 (-)Ensembl
CanFam3.1627,855,702 - 27,950,140 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on ABCC1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12050846
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.