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Gene: CYP1A2 (cytochrome P450 family 1 subfamily A member 2) Canis lupus familiaris
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Symbol: CYP1A2
Name: cytochrome P450 family 1 subfamily A member 2
Description: ENCODES a protein that exhibits estrogen 16-alpha-hydroxylase activity (ortholog); estrogen 2-hydroxylase activity (ortholog); heme binding (ortholog); INVOLVED IN estrogen metabolic process (ortholog); retinol metabolic process (ortholog); PARTICIPATES IN axitinib pharmacokinetics pathway; caffeine pharmacokinetics pathway; clomipramine pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Atrophy (ortholog); breast cancer (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH clofibrate; phenacetin; phenobarbital
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cholesterol 25-hydroxylase; CYPIA2; cytochrome P450 1A2; cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochrome P450-D2; Cytochrome-P450-1A2; DAH2; hydroperoxy icosatetraenoate dehydratase
Orthologs:
Homo sapiens (human) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)  HGNC  Alliance
Mus musculus (house mouse) : Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010322 (cytochrome P450 1A2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975837 (cytochrome P450 1A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969421 (cytochrome P450 1A2)
Sus scrofa (pig) : CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2)
Chlorocebus sabaeus (green monkey) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3037,799,140 - 37,824,135 (+)Ensembl
CanFam3.13037,818,400 - 37,824,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on CYP1A2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12053109
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.