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Gene: SIRT6 (sirtuin 6) Canis lupus familiaris
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Symbol: SIRT6
Name: sirtuin 6
Description: ENCODES a protein that exhibits chromatin binding (inferred); NAD(P)+-protein-arginine ADP-ribosyltransferase activity (inferred); NAD+ binding (inferred); INVOLVED IN base-excision repair (inferred); glucose homeostasis (inferred); histone H3-K9 deacetylation (inferred); PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH amenorrhea (ortholog); Cardiomegaly (ortholog); fatty liver disease (ortholog); FOUND IN nuclear telomeric heterochromatin (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6
Orthologs:
Homo sapiens (human) : SIRT6 (sirtuin 6)  HGNC  Alliance
Mus musculus (house mouse) : Sirt6 (sirtuin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sirt6 (sirtuin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt6 (sirtuin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT6 (sirtuin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt6 (sirtuin 6)
Sus scrofa (pig) : SIRT6 (sirtuin 6)
Chlorocebus sabaeus (African green monkey) : SIRT6 (sirtuin 6)
Heterocephalus glaber (naked mole-rat) : Sirt6 (sirtuin 6)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2055,412,646 - 55,424,944 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12055,412,989 - 55,424,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on SIRT6
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12061965
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.