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Gene: AGO3 (argonaute RISC catalytic component 3) Canis lupus familiaris
Symbol: AGO3
Name: argonaute RISC catalytic component 3
Description: ENCODES a protein that exhibits double-stranded RNA binding (inferred); endoribonuclease activity, cleaving miRNA-paired mRNA (inferred); miRNA binding (inferred); INVOLVED IN gene silencing by RNA (inferred); miRNA loading onto RISC involved in gene silencing by miRNA (inferred); miRNA mediated inhibition of translation (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN condensed nuclear chromosome (inferred); nucleoplasm (inferred); P-body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: argonaute 3, RISC catalytic component; EIF2C3; eukaryotic translation initiation factor 2C, 3; protein argonaute-3
Homo sapiens (human) : AGO3 (argonaute RISC catalytic component 3)  HGNC  Alliance
Mus musculus (house mouse) : Ago3 (argonaute RISC catalytic subunit 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ago3 (argonaute RISC catalytic component 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago3 (argonaute RISC catalytic component 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO3 (argonaute RISC catalytic component 3)
Sus scrofa (pig) : AGO3 (argonaute RISC catalytic component 3)
Chlorocebus sabaeus (African green monkey) : AGO3 (argonaute RISC catalytic component 3)
Heterocephalus glaber (naked mole-rat) : Ago3 (argonaute RISC catalytic component 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl156,145,895 - 6,253,085 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1156,133,303 - 6,253,032 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on AGO3
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12065343
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.