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Gene: MSH2 (mutS homolog 2) Canis lupus familiaris
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Symbol: MSH2
Name: mutS homolog 2
Description: ENCODES a protein that exhibits ADP binding (inferred); ATP binding (inferred); centromeric DNA binding (inferred); INVOLVED IN B cell differentiation (inferred); cell cycle arrest (inferred); determination of adult lifespan (inferred); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; mismatch repair pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); ascending colon cancer (ortholog); B-lymphoblastic leukemia/lymphoma with ETV6-RUNX1 (ortholog); FOUND IN mismatch repair complex (inferred); MutSalpha complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA mismatch repair protein Msh2; mutS homolog 2, colon cancer, nonpolyposis type 1; mutS-like protein 2
Orthologs:
Homo sapiens (human) : MSH2 (mutS homolog 2)  HGNC  Alliance
Mus musculus (house mouse) : Msh2 (mutS homolog 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msh2 (mutS homolog 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msh2 (mutS homolog 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MSH2 (mutS homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msh2 (mutS homolog 2)
Sus scrofa (pig) : MSH2 (mutS homolog 2)
Chlorocebus sabaeus (African green monkey) : MSH2 (mutS homolog 2)
Heterocephalus glaber (naked mole-rat) : Msh2 (mutS homolog 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1049,517,369 - 49,594,210 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11049,517,448 - 49,594,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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More on MSH2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12073611
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.