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Gene: BCL2 (BCL2 apoptosis regulator) Canis lupus familiaris
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Symbol: BCL2
Name: BCL2 apoptosis regulator
Description: ENCODES a protein that exhibits BH3 domain binding (inferred); channel activity (inferred); channel inhibitor activity (inferred); INVOLVED IN actin filament organization (inferred); axon regeneration (inferred); axonogenesis (inferred); PARTICIPATES IN amyotrophic lateral sclerosis pathway; apoptotic cell death pathway; ceramide signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); INTERACTS WITH calcitriol; spironolactone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; BCL-2; BCL2, apoptosis regulator
Orthologs:
Homo sapiens (human) : BCL2 (BCL2 apoptosis regulator)  HGNC  Alliance
Mus musculus (house mouse) : Bcl2 (B cell leukemia/lymphoma 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bcl2 (BCL2, apoptosis regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl2 (BCL2 apoptosis regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL2 (BCL2 apoptosis regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2 (BCL2 apoptosis regulator)
Sus scrofa (pig) : BCL2 (BCL2 apoptosis regulator)
Chlorocebus sabaeus (African green monkey) : BCL2 (BCL2 apoptosis regulator)
Heterocephalus glaber (naked mole-rat) : Bcl2 (BCL2 apoptosis regulator)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl113,731,406 - 13,900,658 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1113,733,849 - 13,900,653 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

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Nomenclature History
 
More on BCL2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12074886
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.