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Gene: IRS1 (insulin receptor substrate 1) Canis lupus familiaris
Symbol: IRS1
Name: insulin receptor substrate 1
CRRD ID: 12078342
Description: ENCODES a protein that exhibits insulin receptor binding (ortholog); insulin-like growth factor receptor binding (ortholog); phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN aging (ortholog); cellular response to angiotensin (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH AIDS Dementia Complex (ortholog); Alzheimer's disease (ortholog); coronary artery disease (ortholog); FOUND IN caveola (ortholog); ciliary basal body (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: insulin receptor substrate 1
Homo sapiens (human) : IRS1 (insulin receptor substrate 1)  HGNC  Alliance
Mus musculus (house mouse) : Irs1 (insulin receptor substrate 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irs1 (insulin receptor substrate 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irs1 (insulin receptor substrate 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IRS1 (insulin receptor substrate 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irs1 (insulin receptor substrate 1)
Sus scrofa (pig) : IRS1 (insulin receptor substrate 1)
Chlorocebus sabaeus (African green monkey) : IRS1 (insulin receptor substrate 1)
Heterocephalus glaber (naked mole-rat) : Irs1 (insulin receptor substrate 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.12539,624,554 - 39,687,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on IRS1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12078342
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.