RNF135 (ring finger protein 135) - Chinchilla Research Resource Database
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Gene: RNF135 (ring finger protein 135) Canis lupus familiaris
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Symbol: RNF135
Name: ring finger protein 135
CRRD ID: 12091265
Description: ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); RIG-I binding (inferred); INVOLVED IN protein polyubiquitination (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); chromosome 17q11.2 deletion syndrome (ortholog); Developmental Disabilities (ortholog); FOUND IN cytoplasmic stress granule (inferred); ribonucleoprotein complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase RNF135
Orthologs:
Homo sapiens (human) : RNF135 (ring finger protein 135)  HGNC  Alliance
Mus musculus (house mouse) : Rnf135 (ring finger protein 135)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf135 (ring finger protein 135)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf135 (ring finger protein 135)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF135 (ring finger protein 135)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf135 (ring finger protein 135)
Sus scrofa (pig) : RNF135 (ring finger protein 135)
Chlorocebus sabaeus (African green monkey) : RNF135 (ring finger protein 135)
Heterocephalus glaber (naked mole-rat) : Rnf135 (ring finger protein 135)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl940,795,297 - 40,808,737 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1940,794,772 - 40,809,022 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
RNF135
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl940,795,297 - 40,808,737 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1940,794,772 - 40,809,022 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
RNF135
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1730,970,984 - 30,999,911 (+)EnsemblGRCh38hg38GRCh38
GRCh381730,968,642 - 30,999,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371729,296,224 - 29,326,929 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361726,322,082 - 26,351,053 (+)NCBINCBI36hg18NCBI36
Celera1726,218,879 - 26,247,850 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1725,508,635 - 25,537,506 (+)NCBIHuRef
CHM1_11729,360,522 - 29,390,158 (+)NCBICHM1_1
Rnf135
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,074,652 - 80,090,581 (+)NCBI
GRCm381180,183,869 - 80,199,755 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,183,851 - 80,199,757 (+)EnsemblGRCm38mm10GRCm38
MGSCv371179,997,374 - 80,013,255 (+)NCBIGRCm37mm9NCBIm37
MGSCv361180,000,067 - 80,015,948 (+)NCBImm8
Celera1189,820,069 - 89,836,208 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1147.59NCBI
Rnf135
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01067,531,989 - 67,551,237 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01067,189,251 - 67,208,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41068,395,227 - 68,413,513 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11068,408,849 - 68,427,136 (+)NCBI
Celera1064,131,815 - 64,150,477 (+)NCBICelera
Cytogenetic Map10q25NCBI
Rnf135
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554817,111,760 - 7,122,800 (+)NCBIChiLan1.0ChiLan1.0
RNF135
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11725,333,945 - 25,358,151 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01725,843,447 - 25,869,874 (-)NCBIMhudiblu_PPA_v0panPan3
Rnf135
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365382,741,308 - 2,757,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF135
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1242,790,187 - 42,808,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11242,793,755 - 42,808,937 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21244,417,921 - 44,431,466 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF135
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1625,678,197 - 25,700,061 (+)Ensembl
ChlSab1.11625,677,632 - 25,700,769 (+)NCBI
Rnf135
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624875221,206 - 231,178 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 5 6 10 6
Low 5 17 6 1 6 6 12 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029317   ⟹   ENSCAFP00000027261
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl940,795,297 - 40,808,737 (-)Ensembl
RefSeq Acc Id: XM_005624827   ⟹   XP_005624884
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1940,794,772 - 40,809,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022423317   ⟹   XP_022279025
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1940,794,772 - 40,805,678 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005624884 (Get FASTA)   NCBI Sequence Viewer  
  XP_022279025 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005624884   ⟸   XM_005624827
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022279025   ⟸   XM_022423317
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000027261   ⟸   ENSCAFT00000029317
Protein Domains
B30.2/SPRY   RING-type

Promoters
RGD ID:13684661
Promoter ID:EPDNEW_C2729
Type:multiple initiation site
Name:RNF135_1
Description:ring finger protein 135
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1940,808,744 - 40,808,804EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018462 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000027261 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029317 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  RNF135_SPRY_PRY_dom UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report cfa:480614 UniProtKB/TrEMBL
NCBI Gene RNF135 ENTREZGENE
Pfam SPRY UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt E2RD88_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:82296 ENTREZGENE