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Gene: FOXO3 (forkhead box O3) Canis lupus familiaris
Symbol: FOXO3
Name: forkhead box O3
Description: ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN antral ovarian follicle growth (inferred); brain morphogenesis (inferred); cellular response to oxidative stress (inferred); PARTICIPATES IN endometrial cancer pathway; insulin signaling pathway; neurotrophic factor signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Alzheimer's disease (ortholog); Carotid Artery Injuries (ortholog); FOUND IN cytosol (inferred); mitochondrial matrix (inferred); mitochondrial outer membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: FKHRL1; forkhead box O3A; forkhead box protein O3; FOXO3A
Homo sapiens (human) : FOXO3 (forkhead box O3)  HGNC  Alliance
Mus musculus (house mouse) : Foxo3 (forkhead box O3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Foxo3 (forkhead box O3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxo3 (forkhead box O3)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXO3 (forkhead box O3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxo3 (forkhead box O3)
Sus scrofa (pig) : FOXO3 (forkhead box O3)
Chlorocebus sabaeus (African green monkey) : FOXO3 (forkhead box O3)
Heterocephalus glaber (naked mole-rat) : Foxo3 (forkhead box O3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1265,552,310 - 65,670,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11265,552,455 - 65,673,467 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on FOXO3
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12096304
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.