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Gene: LRP6 (LDL receptor related protein 6) Canis lupus familiaris
Symbol: LRP6
Name: LDL receptor related protein 6
Description: ENCODES a protein that exhibits coreceptor activity involved in Wnt signaling pathway (inferred); Wnt-activated receptor activity (inferred); Wnt-protein binding (inferred); INVOLVED IN canonical Wnt signaling pathway (inferred); multicellular organism development (inferred); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH coronary artery disease (ortholog); Coronary Artery Disease, Autosomal Dominant 2 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN integral component of membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: low-density lipoprotein receptor-related protein 6
Homo sapiens (human) : LRP6 (LDL receptor related protein 6)  HGNC  Alliance
Mus musculus (house mouse) : Lrp6 (low density lipoprotein receptor-related protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lrp6 (LDL receptor related protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrp6 (LDL receptor related protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : LRP6 (LDL receptor related protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrp6 (LDL receptor related protein 6)
Sus scrofa (pig) : LRP6 (LDL receptor related protein 6)
Chlorocebus sabaeus (African green monkey) : LRP6 (LDL receptor related protein 6)
Heterocephalus glaber (naked mole-rat) : Lrp6 (LDL receptor related protein 6)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl2734,003,539 - 34,161,437 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12734,003,334 - 34,166,334 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on LRP6
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12139753
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.