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Gene: CCN2 (cellular communication network factor 2) Canis lupus familiaris
Symbol: CCN2
Name: cellular communication network factor 2
Description: ENCODES a protein that exhibits insulin-like growth factor binding (inferred); protein C-terminus binding (inferred); INVOLVED IN positive regulation of cell differentiation (inferred); positive regulation of ERK1 and ERK2 cascade (inferred); positive regulation of JNK cascade (inferred); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Aggressive Fibromatosis (ortholog); aortic valve insufficiency (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: connective tissue growth factor; CTGF
Homo sapiens (human) : CCN2 (cellular communication network factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Ccn2 (cellular communication network factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccn2 (cellular communication network factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccn2 (cellular communication network factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCN2 (cellular communication network factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccn2 (cellular communication network factor 2)
Sus scrofa (pig) : CCN2 (cellular communication network factor 2)
Chlorocebus sabaeus (African green monkey) : CCN2 (cellular communication network factor 2)
Heterocephalus glaber (naked mole-rat) : Ccn2 (cellular communication network factor 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl125,507,662 - 25,510,145 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1125,508,082 - 25,511,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on CCN2
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12141372
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.