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Gene: SIRT3 (sirtuin 3) Canis lupus familiaris
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Symbol: SIRT3
Name: sirtuin 3
Description: ENCODES a protein that exhibits NAD+ binding (inferred); NAD-dependent histone deacetylase activity (inferred); sequence-specific DNA binding (inferred); INVOLVED IN aerobic respiration (inferred); histone deacetylation (inferred); negative regulation of peptidyl-lysine acetylation (inferred); PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome (ortholog); Alzheimer's disease (ortholog); congestive heart failure (ortholog); FOUND IN mitochondrial inner membrane (inferred); mitochondrial matrix (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Orthologs:
Homo sapiens (human) : SIRT3 (sirtuin 3)  HGNC  Alliance
Mus musculus (house mouse) : Sirt3 (sirtuin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sirt3 (sirtuin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt3 (sirtuin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT3 (sirtuin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt3 (sirtuin 3)
Sus scrofa (pig) : SIRT3 (sirtuin 3)
Chlorocebus sabaeus (African green monkey) : SIRT3 (sirtuin 3)
Heterocephalus glaber (naked mole-rat) : Sirt3 (sirtuin 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1825,369,382 - 25,388,118 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11825,369,183 - 25,388,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on SIRT3
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12174970
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.