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Gene: PON1 (paraoxonase 1) Canis lupus familiaris
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Symbol: PON1
Name: paraoxonase 1
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); phospholipid binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN aromatic compound catabolic process (ortholog); carboxylic acid catabolic process (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); acute lymphoblastic leukemia (ortholog); Agricultural Workers' Diseases (ortholog); FOUND IN high-density lipoprotein particle (ortholog); intracellular membrane-bounded organelle (ortholog); spherical high-density lipoprotein particle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: serum paraoxonase/arylesterase 1
Orthologs:
Homo sapiens (human) : PON1 (paraoxonase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pon1 (paraoxonase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pon1 (paraoxonase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pon1 (paraoxonase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PON1 (paraoxonase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pon1 (paraoxonase 1)
Sus scrofa (pig) : PON1 (paraoxonase 1)
Chlorocebus sabaeus (African green monkey) : PON1 (paraoxonase 1)
Heterocephalus glaber (naked mole-rat) : Pon1 (paraoxonase 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1420,565,641 - 20,642,985 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11420,565,620 - 20,600,774 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on PON1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12192386
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.