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Gene: MGMT (O-6-methylguanine-DNA methyltransferase) Canis lupus familiaris
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Symbol: MGMT
Name: O-6-methylguanine-DNA methyltransferase
Description: ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); INVOLVED IN DNA dealkylation involved in DNA repair (inferred); methylation (inferred); regulation of cysteine-type endopeptidase activity involved in apoptotic process (inferred); ASSOCIATED WITH Bile Duct Neoplasms (ortholog); Brain Neoplasms (ortholog); breast cancer (ortholog); FOUND IN nucleoplasm (inferred); INTERACTS WITH carmustine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6-O-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase; O-6-methylguanine-DNA-alkyltransferase; O6-alkylguanine-DNA-alkyltransferase; O6-methylguanine-DNA-methyltransferase
Orthologs:
Homo sapiens (human) : MGMT (O-6-methylguanine-DNA methyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Mgmt (O-6-methylguanine-DNA methyltransferase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mgmt (O-6-methylguanine-DNA methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mgmt (O-6-methylguanine-DNA methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : MGMT (O-6-methylguanine-DNA methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mgmt (O-6-methylguanine-DNA methyltransferase)
Sus scrofa (pig) : MGMT (O-6-methylguanine-DNA methyltransferase)
Chlorocebus sabaeus (green monkey) : MGMT (O-6-methylguanine-DNA methyltransferase)
Heterocephalus glaber (naked mole-rat) : Mgmt (O-6-methylguanine-DNA methyltransferase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2838,204,610 - 38,427,380 (+)Ensembl
CanFam3.12838,204,611 - 38,427,482 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on MGMT
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12194335
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.