Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: APP (amyloid beta precursor protein) Canis lupus familiaris
Symbol: APP
Name: amyloid beta precursor protein
CRRD ID: 12199021
Description: ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); apolipoprotein binding (ortholog); chaperone binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of MAPKKK activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 1 (ortholog); Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ortholog); FOUND IN amyloid-beta complex (ortholog); astrocyte projection (ortholog); axon (ortholog); INTERACTS WITH copper atom; copper(0)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ABPP; alzheimer disease amyloid A4 protein homolog; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid precursor protein; beta-amyloid precursor protein
Homo sapiens (human) : APP (amyloid beta precursor protein)  HGNC  Alliance
Mus musculus (house mouse) : App (amyloid beta (A4) precursor protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : App (amyloid beta precursor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : App (amyloid beta precursor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : APP (amyloid beta precursor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : App (amyloid beta precursor protein)
Sus scrofa (pig) : APP (amyloid beta precursor protein)
Chlorocebus sabaeus (African green monkey) : APP (amyloid beta precursor protein)
Heterocephalus glaber (naked mole-rat) : App (amyloid beta precursor protein)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl3121,351,207 - 21,614,337 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13121,351,207 - 21,614,466 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on APP
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12199021
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.