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Gene: MIR125A (microRNA mir-125a) Canis lupus familiaris
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Symbol: MIR125A
Name: microRNA mir-125a
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: cfa-mir-125a; microRNA 125a
Orthologs:
Homo sapiens (human) : MIR125A (microRNA 125a)  HGNC  Alliance
Mus musculus (house mouse) : Mir125a (microRNA 125a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mir125a (microRNA 125a)  Alliance
Sus scrofa (pig) : MIR125A (microRNA mir-125a)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1105,400,270 - 105,400,337 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11105,400,273 - 105,400,332 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences

Additional Information

External Database Links
Nomenclature History
 
More on MIR125A
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12205822
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.