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Gene: SIRT1 (sirtuin 1) Canis lupus familiaris
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Symbol: SIRT1
Name: sirtuin 1
Description: PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; p53 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); INTERACTS WITH nicotinamide; resveratrol
Type: protein-coding
RefSeq Status: MODEL
Also known as: NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1
Orthologs:
Homo sapiens (human) : SIRT1 (sirtuin 1)  HGNC  Alliance
Mus musculus (house mouse) : Sirt1 (sirtuin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sirt1 (sirtuin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt1 (sirtuin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT1 (sirtuin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt1 (sirtuin 1)
Sus scrofa (pig) : SIRT1 (sirtuin 1)
Chlorocebus sabaeus (green monkey) : SIRT1 (sirtuin 1)
Heterocephalus glaber (naked mole-rat) : Sirt1 (sirtuin 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl419,188,675 - 19,218,279 (+)Ensembl
CanFam3.1419,188,616 - 19,220,031 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on SIRT1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12213926
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.