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Gene: KDR (kinase insert domain receptor) Canis lupus familiaris
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Symbol: KDR
Name: kinase insert domain receptor
Description: ENCODES a protein that exhibits protein tyrosine kinase activity (ortholog); vascular endothelial growth factor binding (ortholog); INVOLVED IN aging (ortholog); branching involved in blood vessel morphogenesis (ortholog); branching morphogenesis of an epithelial tube (ortholog); PARTICIPATES IN altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; altered vascular endothelial growth factor signaling pathway involving the main players; bevacizumab pharmacodynamics pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); adenocarcinoma (ortholog); allergic contact dermatitis (ortholog); FOUND IN cell junction (ortholog); cell periphery (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: flk-1; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; VEGFR2
Orthologs:
Homo sapiens (human) : KDR (kinase insert domain receptor)  HGNC  Alliance
Mus musculus (house mouse) : Kdr (kinase insert domain protein receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kdr (kinase insert domain receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdr (kinase insert domain receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : KDR (kinase insert domain receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdr (kinase insert domain receptor)
Sus scrofa (pig) : KDR (kinase insert domain receptor)
Chlorocebus sabaeus (African green monkey) : KDR (kinase insert domain receptor)
Heterocephalus glaber (naked mole-rat) : Kdr (kinase insert domain receptor)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1347,442,764 - 47,485,042 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11347,442,861 - 47,484,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on KDR
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12223867
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.