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Gene: IGFBP3 (insulin like growth factor binding protein 3) Canis lupus familiaris
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Symbol: IGFBP3
Name: insulin like growth factor binding protein 3
Description: ENCODES a protein that exhibits protein tyrosine phosphatase activator activity (inferred); INVOLVED IN negative regulation of protein phosphorylation (inferred); negative regulation of smooth muscle cell migration (inferred); negative regulation of smooth muscle cell proliferation (inferred); PARTICIPATES IN insulin-like growth factor signaling pathway; p53 signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); Acute-Phase Reaction (ortholog); Alzheimer's disease (ortholog); FOUND IN insulin-like growth factor ternary complex (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: insulin-like growth factor-binding protein 3
Orthologs:
Homo sapiens (human) : IGFBP3 (insulin like growth factor binding protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Igfbp3 (insulin-like growth factor binding protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igfbp3 (insulin-like growth factor binding protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp3 (insulin like growth factor binding protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP3 (insulin like growth factor binding protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp3 (insulin like growth factor binding protein 3)
Sus scrofa (pig) : IGFBP3 (insulin like growth factor binding protein 3)
Chlorocebus sabaeus (African green monkey) : IGFBP3 (insulin like growth factor binding protein 3)
Heterocephalus glaber (naked mole-rat) : Igfbp3 (insulin like growth factor binding protein 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl161,021,972 - 1,026,392 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1161,021,855 - 1,027,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on IGFBP3
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12224708
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.