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Gene: NOS3 (nitric oxide synthase 3) Canis lupus familiaris
Symbol: NOS3
Name: nitric oxide synthase 3
Description: ENCODES a protein that exhibits actin monomer binding (inferred); arginine binding (inferred); calmodulin binding (inferred); INVOLVED IN arginine catabolic process (inferred); endothelial cell migration (inferred); nitric oxide biosynthetic process (inferred); PARTICIPATES IN arginine and proline metabolic pathway; doxorubicin pharmacokinetics pathway; eicosanoid signaling pathway; ASSOCIATED WITH acute chest syndrome (ortholog); acute kidney failure (ortholog); acute myeloid leukemia (ortholog); FOUND IN caveola (inferred); cytoskeleton (inferred); Golgi apparatus (inferred); INTERACTS WITH all-trans-retinoic acid; enalapril; icariin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cNOS; constitutive NOS; EC-NOS; endothelial NOS; eNOS; nitric oxide synthase, endothelial; NOS; NOS type III; NOSIII
Homo sapiens (human) : NOS3 (nitric oxide synthase 3)  HGNC  Alliance
Mus musculus (house mouse) : Nos3 (nitric oxide synthase 3, endothelial cell)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nos3 (nitric oxide synthase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nos3 (nitric oxide synthase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS3 (nitric oxide synthase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos3 (nitric oxide synthase 3)
Sus scrofa (pig) : NOS3 (nitric oxide synthase 3)
Chlorocebus sabaeus (green monkey) : NOS3 (nitric oxide synthase 3)
Heterocephalus glaber (naked mole-rat) : Nos3 (nitric oxide synthase 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1615,011,344 - 15,072,277 (+)Ensembl
CanFam3.11615,054,196 - 15,072,454 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on NOS3
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12243345
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.