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Gene: PLN (phospholamban) Canis lupus familiaris
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Symbol: PLN
Name: phospholamban
Description: ENCODES a protein that exhibits ATPase inhibitor activity; identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN negative regulation of ATPase activity; negative regulation of calcium ion import into sarcoplasmic reticulum; negative regulation of calcium ion transmembrane transporter activity; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH atrial fibrillation (ortholog); autistic disorder (ortholog); cardiac arrest (ortholog); FOUND IN membrane (ortholog); protein-containing complex (ortholog); sarcoplasmic reticulum (ortholog); INTERACTS WITH allopurinol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cardiac phospholamban; PLB
Orthologs:
Homo sapiens (human) : PLN (phospholamban)  HGNC  Alliance
Mus musculus (house mouse) : Pln (phospholamban)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pln (phospholamban)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pln (phospholamban)
Pan paniscus (bonobo/pygmy chimpanzee) : PLN (phospholamban)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pln (phospholamban)
Sus scrofa (pig) : PLN (phospholamban)
Chlorocebus sabaeus (African green monkey) : PLN (phospholamban)
Heterocephalus glaber (naked mole-rat) : Pln (phospholamban)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl158,579,145 - 58,590,535 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1158,579,095 - 58,590,541 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on PLN
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12247034
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.