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Gene: AGO4 (argonaute RISC component 4) Canis lupus familiaris
Symbol: AGO4
Name: argonaute RISC component 4
Description: ENCODES a protein that exhibits double-stranded RNA binding (inferred); miRNA binding (inferred); single-stranded RNA binding (inferred); INVOLVED IN male gonad development (inferred); male meiotic nuclear division (inferred); miRNA loading onto RISC involved in gene silencing by miRNA (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN nucleus (inferred); P-body (inferred); RISC complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: argonaute 4, RISC catalytic component; argonaute RISC catalytic component 4; EIF2C4; eukaryotic translation initiation factor 2C, 4; protein argonaute-4
Homo sapiens (human) : AGO4 (argonaute RISC component 4)  HGNC  Alliance
Mus musculus (house mouse) : Ago4 (argonaute RISC catalytic subunit 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ago4 (argonaute RISC component 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago4 (argonaute RISC component 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO4 (argonaute RISC component 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ago4 (argonaute RISC component 4)
Sus scrofa (pig) : AGO4 (argonaute RISC component 4)
Chlorocebus sabaeus (African green monkey) : AGO4 (argonaute RISC component 4)
Heterocephalus glaber (naked mole-rat) : Ago4 (argonaute RISC component 4)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl156,329,413 - 6,356,676 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1156,325,899 - 6,351,748 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on AGO4
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12251798
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.