Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ALOX5 (arachidonate 5-lipoxygenase) Canis lupus familiaris
Analyze
Symbol: ALOX5
Name: arachidonate 5-lipoxygenase
Description: ENCODES a protein that exhibits iron ion binding (inferred); oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (inferred); INVOLVED IN acute inflammatory response (ortholog); inflammatory response (ortholog); leukocyte migration involved in inflammatory response (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH acute kidney failure (ortholog); adenocarcinoma (ortholog); adenoma (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); nucleus (ortholog); INTERACTS WITH zileuton
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: polyunsaturated fatty acid 5-lipoxygenase
Orthologs:
Homo sapiens (human) : ALOX5 (arachidonate 5-lipoxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Alox5 (arachidonate 5-lipoxygenase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alox5 (arachidonate 5-lipoxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alox5 (arachidonate 5-lipoxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX5 (arachidonate 5-lipoxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alox5 (arachidonate 5-lipoxygenase)
Sus scrofa (pig) : ALOX5 (arachidonate 5-lipoxygenase)
Chlorocebus sabaeus (African green monkey) : ALOX5 (arachidonate 5-lipoxygenase)
Heterocephalus glaber (naked mole-rat) : Alox5 (arachidonate 5-lipoxygenase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl282,170,920 - 2,219,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1282,170,920 - 2,218,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ALOX5
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12252833
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.