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Gene: ACTA2 (actin alpha 2, smooth muscle) Canis lupus familiaris
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Symbol: ACTA2
Name: actin alpha 2, smooth muscle
Description: ENCODES a protein that exhibits ATP binding (inferred); INVOLVED IN mesenchyme migration (ortholog); positive regulation of gene expression (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH aortic disease (ortholog); arterial tortuosity syndrome (ortholog); autoimmune lymphoproliferative syndrome (ortholog); FOUND IN cell body (ortholog); cytoplasm (ortholog); filopodium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: actin, alpha 2, smooth muscle, aorta; actin, aortic smooth muscle
Orthologs:
Homo sapiens (human) : ACTA2 (actin alpha 2, smooth muscle)  HGNC  Alliance
Mus musculus (house mouse) : Acta2 (actin, alpha 2, smooth muscle, aorta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acta2 (actin alpha 2, smooth muscle)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acta2 (actin alpha 2, smooth muscle)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTA2 (actin alpha 2, smooth muscle)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acta2 (actin alpha 2, smooth muscle)
Sus scrofa (pig) : ACTA2 (actin alpha 2, smooth muscle)
Chlorocebus sabaeus (African green monkey) : ACTA2 (actin alpha 2, smooth muscle)
Heterocephalus glaber (naked mole-rat) : Acta2 (actin alpha 2, smooth muscle)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2638,700,480 - 38,711,753 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12638,700,434 - 38,714,915 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on ACTA2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12268039
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.