Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TLR4 (toll like receptor 4) Canis lupus familiaris
Symbol: TLR4
Name: toll like receptor 4
Description: ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to retinoic acid (ortholog); defense response to bacterium (ortholog); PARTICIPATES IN titanium dioxide nanoparticle response pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH Acanthamoeba Keratitis (ortholog); Acne Conglobata (ortholog); Acute Coronary Syndrome (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); intrinsic component of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: toll-like receptor 4; Toll-like receptor4 protein
Homo sapiens (human) : TLR4 (toll like receptor 4)  HGNC  Alliance
Mus musculus (house mouse) : Tlr4 (toll-like receptor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tlr4 (toll-like receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr4 (toll like receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR4 (toll like receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr4 (toll like receptor 4)
Sus scrofa (pig) : TLR4 (toll like receptor 4)
Chlorocebus sabaeus (African green monkey) : TLR4 (toll like receptor 4)
Heterocephalus glaber (naked mole-rat) : Tlr4 (toll like receptor 4)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1171,356,390 - 71,367,165 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11171,356,390 - 71,367,166 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on TLR4
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12269767
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.