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Gene: PTGS2 (prostaglandin-endoperoxide synthase 2) Canis lupus familiaris
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Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (ortholog); INVOLVED IN cellular response to non-ionic osmotic stress; negative regulation of apoptotic process; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN cytoplasm; caveola (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; carprofen; etodolac
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: COX-2; cyclooxygenase 2; cyclooxygenase type 2; prostaglandin G/H synthase 2; prostaglandin G/H synthase-2
Orthologs:
Homo sapiens (human) : PTGS2 (prostaglandin-endoperoxide synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Ptgs2 (prostaglandin-endoperoxide synthase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptgs2 (prostaglandin-endoperoxide synthase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Sus scrofa (pig) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Chlorocebus sabaeus (African green monkey) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Heterocephalus glaber (naked mole-rat) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl719,668,082 - 19,674,903 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1719,668,079 - 19,674,903 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

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Nucleotide Sequences
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More on PTGS2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12279597
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.