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Gene: PLCB1 (phospholipase C beta 1) Canis lupus familiaris
Symbol: PLCB1
Name: phospholipase C beta 1
Description: ENCODES a protein that exhibits identical protein binding (ortholog); phosphatidylinositol phospholipase C activity (ortholog); INVOLVED IN cellular response to fluoride (ortholog); cellular response to glyceraldehyde (ortholog); cellular response to ionomycin (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN cytosol (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Homo sapiens (human) : PLCB1 (phospholipase C beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Plcb1 (phospholipase C, beta 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcb1 (phospholipase C beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb1 (phospholipase C beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB1 (phospholipase C beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb1 (phospholipase C beta 1)
Sus scrofa (pig) : PLCB1 (phospholipase C beta 1)
Chlorocebus sabaeus (African green monkey) : PLCB1 (phospholipase C beta 1)
Heterocephalus glaber (naked mole-rat) : Plcb1 (phospholipase C beta 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl2413,322,296 - 13,995,539 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12413,337,285 - 13,996,218 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on PLCB1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12279897
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.