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Gene: AKR1A1 (aldo-keto reductase family 1 member A1) Canis lupus familiaris
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Symbol: AKR1A1
Name: aldo-keto reductase family 1 member A1
Description: ENCODES a protein that exhibits glucuronolactone reductase activity (inferred); L-glucuronate reductase activity (inferred); oxidoreductase activity (inferred); INVOLVED IN cellular detoxification of aldehyde (inferred); daunorubicin metabolic process (inferred); doxorubicin metabolic process (inferred); PARTICIPATES IN doxorubicin pharmacokinetics pathway; gluconeogenesis pathway; glycolysis pathway; ASSOCIATED WITH breast cancer (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN apical plasma membrane (inferred); synapse (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alcohol dehydrogenase [NADP(+)]
Orthologs:
Homo sapiens (human) : AKR1A1 (aldo-keto reductase family 1 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Akr1a1 (aldo-keto reductase family 1, member A1 (aldehyde reductase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Akr1a1 (aldo-keto reductase family 1 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akr1a1 (aldo-keto reductase family 1 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKR1A1 (aldo-keto reductase family 1 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr1a1 (aldo-keto reductase family 1 member A1)
Sus scrofa (pig) : AKR1A1 (aldo-keto reductase family 1 member A1)
Chlorocebus sabaeus (African green monkey) : AKR1A1 (aldo-keto reductase family 1 member A1)
Heterocephalus glaber (naked mole-rat) : Akr1a1 (aldo-keto reductase family 1 member A1)
more info ...
Related Pseudogenes: LOC475374  
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1514,742,012 - 14,808,592 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11514,792,398 - 14,808,805 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model



Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on AKR1A1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12283459
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-04-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.