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Gene: TREX1 (three prime repair exonuclease 1) Canis lupus familiaris
Symbol: TREX1
Name: three prime repair exonuclease 1
Description: ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN adaptive immune response (ortholog); cellular response to DNA damage stimulus (ortholog); cellular response to organic substance (ortholog); PARTICIPATES IN DNA replication pathway; G2/M DNA damage checkpoint pathway; ASSOCIATED WITH Aicardi-Goutieres syndrome (ortholog); Aicardi-Goutieres Syndrome 1 (ortholog); brain disease (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: three-prime repair exonuclease 1
Homo sapiens (human) : TREX1 (three prime repair exonuclease 1)  HGNC  Alliance
Mus musculus (house mouse) : Trex1 (three prime repair exonuclease 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Trex1 (three prime repair exonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trex1 (three prime repair exonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TREX1 (three prime repair exonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trex1 (three prime repair exonuclease 1)
Sus scrofa (pig) : TREX1 (three prime repair exonuclease 1)
Chlorocebus sabaeus (African green monkey) : TREX1 (three prime repair exonuclease 1)
Heterocephalus glaber (naked mole-rat) : Trex1 (three prime repair exonuclease 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl2040,624,891 - 40,626,906 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12040,624,845 - 40,626,840 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on TREX1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12294921
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.