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Gene: AGO2 (argonaute RISC catalytic component 2) Canis lupus familiaris
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Symbol: AGO2
Name: argonaute RISC catalytic component 2
Description: ENCODES a protein that exhibits endoribonuclease activity, cleaving siRNA-paired mRNA (inferred); metal ion binding (inferred); miRNA binding (inferred); INVOLVED IN gene silencing by RNA (inferred); miRNA mediated inhibition of translation (inferred); mRNA cleavage involved in gene silencing by miRNA (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); malignant mesothelioma (ortholog); myeloid leukemia (ortholog); FOUND IN mRNA cap binding complex (inferred); nucleus (inferred); P-body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: argonaute 2, RISC catalytic component; EIF2C2; eukaryotic translation initiation factor 2C, 2; protein argonaute-2
Orthologs:
Homo sapiens (human) : AGO2 (argonaute RISC catalytic component 2)  HGNC  Alliance
Mus musculus (house mouse) : Ago2 (argonaute RISC catalytic subunit 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ago2 (argonaute RISC catalytic component 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago2 (argonaute RISC catalytic component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO2 (argonaute RISC catalytic component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ago2 (argonaute RISC catalytic component 2)
Sus scrofa (pig) : AGO2 (argonaute RISC catalytic component 2)
Chlorocebus sabaeus (African green monkey) : AGO2 (argonaute RISC catalytic component 2)
Heterocephalus glaber (naked mole-rat) : Ago2 (argonaute RISC catalytic component 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1335,180,912 - 35,268,577 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11335,169,243 - 35,230,252 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

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Nomenclature History
 
More on AGO2
NCBI Gene
Ensembl Gene
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CRRD Object Information
CRRD ID: 12319222
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.