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Gene: P2RY12 (purinergic receptor P2Y12) Canis lupus familiaris
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Symbol: P2RY12
Name: purinergic receptor P2Y12
Description: ENCODES a protein that exhibits G protein-coupled adenosine receptor activity (inferred); G protein-coupled ADP receptor activity (inferred); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); calcium ion transmembrane transport (ortholog); calcium-mediated signaling (ortholog); PARTICIPATES IN clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; ticlopidine pharmacodynamics pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Lung Injury (ortholog); arteriosclerosis (ortholog); FOUND IN basal plasma membrane (ortholog); caveola (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: P2Y purinoceptor 12; P2Y12; P2Y12 platelet ADP receptor
Orthologs:
Homo sapiens (human) : P2RY12 (purinergic receptor P2Y12)  HGNC  Alliance
Mus musculus (house mouse) : P2ry12 (purinergic receptor P2Y, G-protein coupled 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : P2ry12 (purinergic receptor P2Y12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2ry12 (purinergic receptor P2Y12)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RY12 (purinergic receptor P2Y12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2ry12 (purinergic receptor P2Y12)
Sus scrofa (pig) : P2RY12 (purinergic receptor P2Y12)
Chlorocebus sabaeus (African green monkey) : P2RY12 (purinergic receptor P2Y12)
Heterocephalus glaber (naked mole-rat) : P2ry12 (purinergic receptor P2Y12)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2345,909,485 - 45,910,526 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12345,908,574 - 45,954,675 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on P2RY12
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12321621
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.