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Gene: F2 (coagulation factor II, thrombin) Canis lupus familiaris
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Symbol: F2
Name: coagulation factor II, thrombin
Description: ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); regulation of cytosolic calcium ion concentration (ortholog); regulation of gene expression (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Acquired Angioedema (ortholog); Acute Coronary Syndrome (ortholog); Acute Lung Injury (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: prothrombin
Orthologs:
Homo sapiens (human) : F2 (coagulation factor II, thrombin)  HGNC  Alliance
Mus musculus (house mouse) : F2 (coagulation factor II)  MGI  Alliance
Rattus norvegicus (Norway rat) : F2 (coagulation factor II)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F2 (coagulation factor II, thrombin)
Pan paniscus (bonobo/pygmy chimpanzee) : F2 (coagulation factor II, thrombin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F2 (coagulation factor II, thrombin)
Sus scrofa (pig) : F2 (coagulation factor II, thrombin)
Heterocephalus glaber (naked mole-rat) : F2 (coagulation factor II, thrombin)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1842,782,751 - 42,799,459 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11842,782,744 - 42,799,531 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

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More on F2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12322578
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.