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Gene: PTPN11 (protein tyrosine phosphatase non-receptor type 11) Canis lupus familiaris
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Symbol: PTPN11
Name: protein tyrosine phosphatase non-receptor type 11
Description: ENCODES a protein that exhibits cadherin binding (inferred); hydrolase activity (inferred); insulin receptor binding (inferred); INVOLVED IN abortive mitotic cell cycle (inferred); activation of MAPK activity (inferred); atrioventricular canal development (inferred); PARTICIPATES IN chronic myeloid leukemia pathway; epidermal growth factor/neuregulin signaling pathway; erythropoietin signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); adenocarcinoma (ortholog); aortic valve disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); SHP-2; tyrosine-protein phosphatase non-receptor type 11
Orthologs:
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,989,218 - 10,072,245 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog Cytomap26 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on PTPN11
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12326459
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.