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Gene: FURIN (furin, paired basic amino acid cleaving enzyme) Canis lupus familiaris
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Symbol: FURIN
Name: furin, paired basic amino acid cleaving enzyme
CRRD ID: 12332502
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); peptidase activity (ortholog); INVOLVED IN aging (ortholog); positive regulation of cell migration (ortholog); positive regulation of transforming growth factor beta receptor signaling pathway (ortholog); PARTICIPATES IN glypican signaling pathway; hypoxia inducible factor pathway; Notch signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); arteriosclerosis (ortholog); Bloom syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi cisterna (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: furin
Orthologs:
Homo sapiens (human) : FURIN (furin, paired basic amino acid cleaving enzyme)  HGNC  Alliance
Mus musculus (house mouse) : Furin (furin (paired basic amino acid cleaving enzyme))  MGI  Alliance
Rattus norvegicus (Norway rat) : Furin (furin (paired basic amino acid cleaving enzyme))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Furin (furin, paired basic amino acid cleaving enzyme)
Pan paniscus (bonobo/pygmy chimpanzee) : FURIN (furin, paired basic amino acid cleaving enzyme)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Furin (furin, paired basic amino acid cleaving enzyme)
Sus scrofa (pig) : FURIN (furin, paired basic amino acid cleaving enzyme)
Chlorocebus sabaeus (African green monkey) : FURIN (furin, paired basic amino acid cleaving enzyme)
Heterocephalus glaber (naked mole-rat) : Furin (furin, paired basic amino acid cleaving enzyme)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl353,358,045 - 53,365,423 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1353,357,491 - 53,368,285 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on FURIN
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12332502
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.