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Gene: SLC8A1 (solute carrier family 8 member A1) Canis lupus familiaris
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Symbol: SLC8A1
Name: solute carrier family 8 member A1
Description: ENCODES a protein that exhibits calcium ion binding; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration; calcium:sodium antiporter activity; INVOLVED IN calcium ion transmembrane transport; sodium ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); Cardiomegaly (ortholog); FOUND IN intrinsic component of plasma membrane; INTERACTS WITH allopurinol; amiodarone; calcium atom
Type: protein-coding
RefSeq Status: INFERRED
Also known as: cardiac sarcolemmal sodium-calcium exchanger; Na(+)/Ca(2+)-exchange protein 1; Na+/Ca2+ exchanger; NCX1; sodium/calcium exchanger 1; solute carrier family 8 member 1
Orthologs:
Homo sapiens (human) : SLC8A1 (solute carrier family 8 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc8a1 (solute carrier family 8 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc8a1 (solute carrier family 8 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC8A1 (solute carrier family 8 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc8a1 (solute carrier family 8 member A1)
Sus scrofa (pig) : SLC8A1 (solute carrier family 8 member A1)
Chlorocebus sabaeus (African green monkey) : SLC8A1 (solute carrier family 8 member A1)
Heterocephalus glaber (naked mole-rat) : Slc8a1 (solute carrier family 8 member A1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1732,005,245 - 32,307,700 (-)Ensembl
CanFam3.11732,004,207 - 32,381,399 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on SLC8A1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12334269
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.