Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SLC8A1 (solute carrier family 8 member A1) Canis lupus familiaris
Symbol: SLC8A1
Name: solute carrier family 8 member A1
Description: ENCODES a protein that exhibits calcium ion binding; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration; calcium:sodium antiporter activity; INVOLVED IN calcium ion transmembrane transport; sodium ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); Cardiomegaly (ortholog); FOUND IN intrinsic component of plasma membrane; INTERACTS WITH allopurinol; amiodarone; calcium atom
Type: protein-coding
RefSeq Status: INFERRED
Also known as: cardiac sarcolemmal sodium-calcium exchanger; Na(+)/Ca(2+)-exchange protein 1; Na+/Ca2+ exchanger; NCX1; sodium/calcium exchanger 1; solute carrier family 8 member 1
Homo sapiens (human) : SLC8A1 (solute carrier family 8 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc8a1 (solute carrier family 8 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc8a1 (solute carrier family 8 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC8A1 (solute carrier family 8 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc8a1 (solute carrier family 8 member A1)
Sus scrofa (pig) : SLC8A1 (solute carrier family 8 member A1)
Chlorocebus sabaeus (African green monkey) : SLC8A1 (solute carrier family 8 member A1)
Heterocephalus glaber (naked mole-rat) : Slc8a1 (solute carrier family 8 member A1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1732,005,245 - 32,307,700 (-)Ensembl
CanFam3.11732,004,207 - 32,381,399 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on SLC8A1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12334269
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.