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Gene: NLRP3 (NLR family pyrin domain containing 3) Canis lupus familiaris
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Symbol: NLRP3
Name: NLR family pyrin domain containing 3
Description: ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); sequence-specific DNA binding (inferred); INVOLVED IN interleukin-1 production (ortholog); leukocyte migration involved in inflammatory response (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH acne (ortholog); alcoholic hepatitis (ortholog); Anaphylaxis (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NACHT, LRR and PYD domains-containing protein 3
Orthologs:
Homo sapiens (human) : NLRP3 (NLR family pyrin domain containing 3)  HGNC  Alliance
Mus musculus (house mouse) : Nlrp3 (NLR family, pyrin domain containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nlrp3 (NLR family, pyrin domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlrp3 (NLR family pyrin domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP3 (NLR family pyrin domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp3 (NLR family pyrin domain containing 3)
Sus scrofa (pig) : NLRP3 (NLR family pyrin domain containing 3)
Chlorocebus sabaeus (African green monkey) : NLRP3 (NLR family pyrin domain containing 3)
Heterocephalus glaber (naked mole-rat) : Nlrp3 (NLR family pyrin domain containing 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl8253,407 - 313,059 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.18251,776 - 313,290 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on NLRP3
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12364239
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.