ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase) - Chinchilla Research Resource Database
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Gene: ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase) Canis lupus familiaris
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Symbol: ALKBH2
Name: alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
CRRD ID: 12381808
Description: ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (ortholog); FOUND IN nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: alkB, alkylation repair homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; DNA oxidative demethylase ALKBH2
Orthologs:
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2617,911,763 - 17,917,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12617,911,892 - 17,918,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA)

References

Genomics

Comparative Map Data
ALKBH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2617,911,763 - 17,917,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12617,911,892 - 17,918,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ALKBH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12109,088,188 - 109,093,631 (-)EnsemblGRCh38hg38GRCh38
GRCh3812109,088,189 - 109,093,631 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712109,525,993 - 109,531,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,010,379 - 108,015,628 (-)NCBINCBI36hg18NCBI36
Celera12109,149,917 - 109,155,219 (-)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12106,544,162 - 106,549,711 (-)NCBIHuRef
CHM1_112109,493,646 - 109,498,943 (-)NCBICHM1_1
Alkbh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,261,987 - 114,269,293 (-)NCBI
GRCm385114,123,926 - 114,131,233 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,123,926 - 114,128,218 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,573,943 - 114,578,185 (-)NCBIGRCm37mm9NCBIm37
MGSCv365114,384,933 - 114,389,175 (-)NCBImm8
Celera5111,225,796 - 111,230,044 (-)NCBICelera
Cytogenetic Map5FNCBI
Alkbh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01248,257,575 - 48,262,244 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,257,609 - 48,262,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,039,893 - 50,044,572 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,531,682 - 43,536,317 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,392,394 - 43,399,689 (+)NCBI
Celera1244,100,824 - 44,105,459 (+)NCBICelera
Cytogenetic Map12q16NCBI
Alkbh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,255,292 - 10,265,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,258,736 - 10,265,100 (-)NCBIChiLan1.0ChiLan1.0
ALKBH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112110,058,507 - 110,068,225 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,058,507 - 110,063,946 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012106,664,678 - 106,670,558 (-)NCBIMhudiblu_PPA_v0panPan3
Alkbh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936769904,129 - 908,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALKBH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,760,505 - 41,766,090 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,760,427 - 41,766,990 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,326,105 - 44,331,765 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALKBH2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl11104,288,454 - 104,298,196 (-)Ensembl
ChlSab1.111104,292,528 - 104,298,500 (-)NCBI
Alkbh2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474712,249,333 - 12,259,248 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 2 22 6 6 6 6 2 12 8 10 6
Below cutoff 3 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000017727   ⟹   ENSCAFP00000016410
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2617,911,763 - 17,917,788 (+)Ensembl
RefSeq Acc Id: XM_005636332   ⟹   XP_005636389
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,242 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005636333   ⟹   XP_005636390
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,042 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014107877   ⟹   XP_013963352
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,242 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014107878   ⟹   XP_013963353
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,269 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022410544   ⟹   XP_022266252
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,242 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022410546   ⟹   XP_022266254
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,911,892 - 17,918,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_534719   ⟹   XP_534719
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12617,914,075 - 17,918,911 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005636390   ⟸   XM_005636333
- UniProtKB: E2R042 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_534719   ⟸   XM_534719
- UniProtKB: E2R042 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013963353   ⟸   XM_014107878
- UniProtKB: E2R042 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005636389   ⟸   XM_005636332
- UniProtKB: E2R042 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013963352   ⟸   XM_014107877
- UniProtKB: E2R042 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022266254   ⟸   XM_022410546
- Sequence:
RefSeq Acc Id: XP_022266252   ⟸   XM_022410544
- Sequence:
RefSeq Acc Id: ENSCAFP00000016410   ⟸   ENSCAFT00000017727
Protein Domains
Fe2OG dioxygenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011152 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000016410 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000017727 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.590 UniProtKB/TrEMBL
InterPro AlkB-like UniProtKB/TrEMBL
  AlkB-like_sf UniProtKB/TrEMBL
  Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
NCBI Gene ALKBH2 ENTREZGENE
Pfam 2OG-FeII_Oxy_2 UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
UniProt E2R042 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:37803 ENTREZGENE