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Gene: LTA (lymphotoxin alpha) Canis lupus familiaris
Symbol: LTA
Name: lymphotoxin alpha
Description: ENCODES a protein that exhibits cytokine activity (inferred); tumor necrosis factor receptor binding (inferred); INVOLVED IN defense response to Gram-positive bacterium (inferred); humoral immune response (inferred); lymph node development (inferred); PARTICIPATES IN interleukin-4 signaling pathway; type 1 diabetes mellitus pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); allergic hypersensitivity disease (ortholog); arteriosclerosis (ortholog); FOUND IN extracellular space (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LT-alpha; lymphotoxin alpha (TNF superfamily, member 1); lymphotoxin-alpha; TNF beta; TNF-beta; TNFB; TNFSF1; TNLG1E; tumor necrosis factor ligand 1E; tumor necrosis factor ligand superfamily member 1
Homo sapiens (human) : LTA (lymphotoxin alpha)  HGNC  Alliance
Mus musculus (house mouse) : Lta (lymphotoxin A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lta (lymphotoxin alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lta (lymphotoxin alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LTA (lymphotoxin alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lta (lymphotoxin alpha)
Sus scrofa (pig) : LTA (lymphotoxin alpha)
Heterocephalus glaber (naked mole-rat) : Lta (lymphotoxin alpha)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl121,071,192 - 1,073,067 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1121,070,608 - 1,073,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on LTA
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12382647
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.